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Does the introduction explain the objective of the research presented in the preprint?

Yes

It clearly describes how the pearl has dual roles in resisting SARS-CoV-2 infection and its complications.

Are the methods well-suited for this research?

Somewhat appropriate

Are the conclusions supported by the data?

Highly supported

Their conclusions are supported. Their figures show how the study was conducted and results match the conclusion.

Are the data presentations, including visualizations, well-suited to represent the data?

Somewhat appropriate and clear

How clearly do the authors discuss, explain, and interpret their findings and potential next steps for the research?

Neither clearly nor unclearly

Is the preprint likely to advance academic knowledge?

Somewhat likely

This pearl could be a scientific advancements to treat COVID infections.

Would it benefit from language editing?

No

Would you recommend this preprint to others?

Yes, it’s of high quality

Is it ready for attention from an editor, publisher or broader audience?

Yes, as it is

Competing interests

The author declares that they have no competing interests.