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PREreviews of A conserved local structural motif controls the kinetics of PTP1B catalysis

1 PREreview

  1. PREreview by CJ San Felipe

    PTP1b has been an attractive target for drug development due to its essential role in several cellular pathways and diseases such as type 2 diabetes. Focus has been paid to identifying allosteric sites that regulate catalytic activity via altering the dynamics of the active site WPD loop. However, …

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