Rédiger un PREreview

This transdisciplinary work delineates the epidemiological and judicial history of a decade of hidden bovine epidemics (tuberculosis and brucellosis) within the Italian territory, analyzing the systematic evasion of differential diagnosis in human medicine. Through the convergence of judicial acts, healthcare ordinances, and molecular biology evidence (including transcriptomic data from Microarrays and kinetic models from the Centre for Bacterial Cell Biology at Newcastle University), this paper demonstrates how mycobacteria stably transition into pleomorphic variants lacking a conventional cell wall (Cell Wall-Deficient / L-forms).

These shape-shifting biological entities evade traditional culture-based screenings and overcome industrial thermal barriers during dairy pasteurization (as tracked in EFSA's BIOHAZ risk profiles), acting as a covert pathogen driver. Finally, the investigation maps the impact of such bioproducts and alterations of the zeta potential in biological fluids among youth populations—assumed as the national epidemiological thermometer—providing the rational and biophysical basis for understanding systemic pathologies, cardiomyopathies, and anomalous clotting phenomena (White Clots) classified under the S.P.A.M. research line.