Introduction: The superficial palmar branch of the radial artery (SPBRA) typically originates 10 to 20 mm proximal to the distal wrist crease, before the radial artery winds around the carpal bones toward the dorsum of the hand. From its origin, the SPBRA courses along the palmar aspect of the hand, traverses the fibers of the thenar muscles, and anastomoses with the ulnar artery to form the superficial palmar arch. Anatomical variations of this branch are described in the literature; given its potential as a vascular pedicle for thenar flaps in the reconstruction of distal finger and hand injuries, knowledge of its morphology is indispensable for surgical safety. Objective: To report a proximal origin of the SPBRA and discuss its possible clinical and surgical implications. Case Report: During routine dissection, an anatomical variation in the origin of the SPBRA was identified in a right forearm disarticulated at the elbow level. The radial artery followed its usual course in the anterior forearm until it prematurely emitted the SPBRA in the distal third, 61.05 mm proximal to the wrist joint, characterizing a high origin compared to the pattern described in the literature. The branch directed itself obliquely in a distal and medial direction, penetrated the fibers of the abductor pollicis brevis muscle, and, after this intramuscular segment, anastomosed with the ulnar artery to form the superficial palmar arch. The total length of the SPBRA was 92.68 mm. Conclusion: The high origin of the SPBRA is a rare anatomical variation of great clinical relevance, the recognition of which is fundamental in planning surgical and reconstructive procedures of the hand, especially in the design of thenar flaps. In addition to corroborating previous literature findings, the present study contributes an unprecedented measurement of the distance between the high origin of the branch and the wrist joint, providing relevant data for the anatomical characterization of this variation.