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This study was aimed to investigate the effect of lifestyle behaviors, traditional oral health practices, dietary patterns, and stress-related conditions on the oral health status of schoolchildren at NJV Government School, Karachi, based on questionnaire responses and clinical examination findings. Among 142 students between 10 and 16 years old, a quantitative cross-sectional study was taken at one point in time. Rather than relay on self-reports, actual oral exams followed World Health Organization protocols. These examinations recorded decayed, missing, or filled teeth (DMFT), gum health, presence of dental plaque, bad breath, and tooth discomfort. Though surveys provided behavior data, clinical findings confirmed the results based on physical signs. Statistical analyses were performed by using SPSS software, Including both descriptive and inferential methods, with statistical significance set at p<0.05. Among the study participants, 46.5% had dental caries, 41.5% reported tooth sensitivity, and 38% exhibited gingival bleeding. A statistically significant association was observed between brushing frequency and dental caries (p=0.007). In contrast, dental caries showed no significant relationship with betel nut chewing, miswak use, or snack consumption. Gingival bleeding was significantly associated with tooth sensitivity (p=0.027). The conventional therapies and lifestyle habits indicated no significant interaction with the evaluated oral health outcomes. Daily hygiene practices were the main factor influencing schoolchildren's oral health status, with brushing frequency appearing as a significant predictor of caries experience. The majority of lifestyle factors and conventional oral practices have no effect.