This study presents a qualitative analysis of the socio-economic and health impacts of recurrent flooding in Aweil East and South, South Sudan, based on Focus Group Discussions (FGDs) with women, elders, farmers, fishers, internally displaced persons (IDPs), returnees, and persons with disabilities (PWDs). The findings reveal that flooding is not just an environmental event but a catalyst that exacerbates pre-existing vulnerabilities and deepens social inequalities. Participants reported the widespread destruction of livelihoods, severe disruption of essential services, and an increase in physical and mental health risks. The study also highlights profound social injustices, including the economic disempowerment and gender-based violence faced by women, the systemic exclusion of elders and PWDs from disaster response, and the precarious existence of displaced persons. The findings underscore the urgent need for inclusive, community-driven, and gender-sensitive disaster preparedness and recovery strategies that prioritize dignity, resilience, and justice for all.