PREreview estructurada del Early Metabolic Alterations in Cerebrospinal Fluid Fatty Acid Profiles Linked to Cognitive Decline and All-Cause Dementia

Does the introduction explain the objective of the research presented in the preprint?

Yes

Are the methods well-suited for this research?

Somewhat appropriate

The method was somewhat appropriate because the presentation of the method wasn't detailed enough. The authors need to give detailed information on the reason for the study site and the study design used. Also, the steps to arriving at their sampling weren't properly presented. The ethical approval is also missing with a significant absence of inclusion and exclusion criteria. The data type is not presented (Primary or secondary). No detailed information on the data collection tools, the data collectors, or how the details were abstracted. The data storage and management were also missing in the method section

Are the conclusions supported by the data?

Somewhat supported

It was somewhat appropriate owing to the sample size and the study design used which might not be the true evidence of their findings.

Are the data presentations, including visualizations, well-suited to represent the data?

Highly appropriate and clear

How clearly do the authors discuss, explain, and interpret their findings and potential next steps for the research?

Very clearly

Is the preprint likely to advance academic knowledge?

Highly likely

Would it benefit from language editing?

No

A minor grammatical error and authors need to address the paragraphs of their Preprint

Would you recommend this preprint to others?

Yes, but it needs to be improved

Is it ready for attention from an editor, publisher or broader audience?

Yes, after minor changes

Competing interests

The authors declare that they have no competing interests.