Saltar al contenido principal

Escribe una PREreview

BPGA: an interactive Shiny application for basic population genetic analysis of genotype data

Publicada
Servidor
EcoEvoRxiv
DOI
10.32942/x2059r

Background: Population structure and ancestry inference are routine in human genetics, yet remain inconvenient for non experts because canonical tools (PLINK, GCTA, ADMIXTURE) require command line expertise and careful data management. Results: BPGA (Basic Population Genetic Analysis) is an open source R/Shiny application that provides an interactive workflow for educational and exploratory population genetic analyses on datasets in PLINK binary format. BPGA executes LD pruned PCA, genome wide Fst scans, and ADMIXTURE clustering from a guided interface, and it can optionally merge user data with curated worldwide reference panels (1000 Genomes Project and Human Genome Diversity Project). The app produces publication ready figures (PNG/HTML), interactive views (plotly/leaflet), and preserves logs for reproducibility. Availability: Source code is available at https://github.com/jfibla/BPGA a Shiny app to perform Basic Population Genetic Analysis under the Apache 2.0 license. A hosted demo is also available at . Conclusions: BPGA lowers the barrier between raw genotype data and interpretable population genetic summaries for research and teaching, while keeping analyses transparent and reproducible.

Puedes escribir una PREreview de BPGA: an interactive Shiny application for basic population genetic analysis of genotype data. Una PREreview es una revisión de un preprint y puede variar desde unas pocas oraciones hasta un extenso informe, similar a un informe de revisión por pares organizado por una revista.

Antes de comenzar

Te pediremos que inicies sesión con tu ORCID iD. Si no tienes un iD, puedes crear uno.

¿Qué es un ORCID iD?

Un ORCID iD es un identificador único que te distingue de otros/as con tu mismo nombre o uno similar.

Comenzar ahora