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This paper introduces a hybrid design framework that makes Christopher Alexander’s Pattern Language actionable through modern AI. Enabled by advanced large language models (LLMs), this method allows real-time synthesis of design patterns, making complex architectural choices accessible and comprehensible to stakeholders without specialized architectural knowledge. A lightweight, web-based tool lets project teams rapidly assemble context-specific subsets of Alexander’s 253 patterns, reducing a traditionally unwieldy 1,166-page corpus to a concise, shareable list. Demonstrated through a case study of a university department building, this method results in environments that are psychologically welcoming, fostering health, productivity, and emotional well-being. LLMs translate these curated patterns into vivid, experiential narratives—complete with neuro-scientifically informed ornamentation. By bridging abstract design principles and concrete human experience, this approach democratizes architectural planning grounded on Alexander’s human-centered ethos, and opens new avenues for participatory, evidence-based design.