Summary:
This preprint fills a gap in the literature to date by investigating the genetic diversity of RH5-Interacting Protein (PfRIPR) using 89 blood samples from Senegal. This is a highly relevant and timely study given that PfRIPR, which is part of the PTRAMP—CSS—RIPR—CyRPA—RH5 (PCRCR) complex…
Summary and Overall Impression:
Overall, this paper presents an in-depth structural analysis of potential SNPs that may cause issues in vaccines targeting the RIPR protein. The authors perform deep amplicon sequencing and successfully identify 15 novel SNPs, in addition to 11 previously described…
Summary and Overall Impression:
Overall, this paper presents an in-depth structural analysis of potential SNPs that may cause issues in vaccines targeting the RIPR protein. The authors perform deep amplicon sequencing and successfully identify 15 novel SNPs, in addition to 11 previously described…