Over the past 50 years, scientific interest in electromagnetic field-biology interactions has flourished. Important experimental observations and mathematical hypotheses remain central to academic debate. Adey [1, 2] and Blackman [3, 4] found that specific electromagnetic frequencies affect calcium transport in cells. To explain this phenomenon, Liboff introduced ion cyclotron resonance-like (ICR-like) theory [5, 8-10, 32], proposing a specific mechanism for ion modulation. Preparata and Del Giudice introduced quantum electrodynamics (QED) [26-28], offering controversial quantum-level explanations that complement classical models. Lucia and NASA contributed further with thermomagnetic resonance [69-74] and experimental observations [76]. Together, these hypotheses have partially clarified how weak electromagnetic fields interact with cells and suggest possible parallel endogenous mechanisms. The aim of this narrative review is to provide a clear and logical framework for understanding biological events, both those that arise naturally within biology and those that can be initiated externally through the application of electromagnetic fields. Since electromagnetism is one of the 4 fundamental forces, this peculiarity deserves careful scientific attention.