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The next generation of observatories (Euclid, JWST, SKA) will soon deliver data of unprecedented quality, offering the first opportunity to probe physical realms where current theoretical models remain silent. This study presents three definitive, testable predictions for phenomena that the prevailing ΛCDM cosmological and planetary equilibrium models cannot describe. The predictions are: (i) a weak-lensing shear residual of δγ ≈ 1.7 × 10⁻⁵ ± 2 × 10⁻⁶ to be detected by Euclid in November 2025; (ii) an oxygen fugacity anomaly of Δlog f_O ≈ 0.32 ± 0.05 for the exoplanet K2-18b from JWST in October 2025; and (iii) an unexplained neutral hydrogen line broadening of Δv ≈ 0.47 ± 0.06 km/s from the SKA in December 2025. Empirical verification of these predictions will provide a decisive benchmark for the development of the next generation of physical models, potentially necessitating a paradigm shift in our understanding of dark energy, planetary interiors, and dark matter interactions.