Invasive Lobular Carcinoma Metastases to the Female Genital Tract. A Review of Case Reports and Case Series
Authored by Nektarios I. Koufopoulos, Abraham Pouliakis, Menelaos G. Samaras, Kostantinos Skarentzos, Theofanis Nastos, Ioannis Boutas, Adamantia Kontogeorgi, Magda Zanelli, Andrea Palicelli, Maurizio Zizzo, Giuseppe Broggi, Rosario Caltabiano, Serena Salzano, Dimitrios Goutas, Ioannis S. Pateras, John Syrios, Amanda Psyrri, Nikolaos Arkadopoulos, and Ioannis G. Panayiotides
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Preprints.org
DOI
10.20944/preprints202508.1349.v1
Invasive lobular carcinoma (ILC) is the most common special type of breast carcinoma, accounting for 5-15% of all breast carcinoma cases. It exhibits several unique features in morphology, clinical behavior, radiological features, molecular characteristics, and metastatic pattern. The latter differs from that of invasive breast carcinoma of no special type with ILC metastases to the peritoneum, gastrointestinal tract, and female genital tract being more frequent. We herewith review the demographic, clinicopathological, and therapeutic aspects of ILC metastases to the female genital tract and discuss separately the differential diagnosis and prognosis for each anatomic location of the female genital tract.
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