HHMI Transparent and Accountable Peer Review Training Program
HHMI is a biomedical research organization and philanthropy that supports a vibrant community of researchers,
educators, students, and professionals. Together, we’re unlocking the fundamentals of biology and building an
open, inclusive future for science.
As part of a newly developed training pilot, participating graduate students and postdocs in HHMI labs will
learn to conduct peer review in a manner that is constructive and transparent.
Club leads
Anna Hatch and Darian Carroll
PREreviews
Ink Bison reviewed
Hepatocyte Circadian Clocks Control Cholesterol Metabolism and Protect From Metabolic Dysfunction-Associated Steatohepatitis (MASH)
Endocrine and Autonomic Systems Endocrinology, Diabetes and Metabolism Physiology
Review published
December 19, 2025
Preprint server
bioRxiv
Fisher Cherry and 1 other author reviewed
Insulin resistance alters cortical inhibitory neurons and microglia to exacerbate Alzheimer’s knock-in mouse phenotypes
Molecular Biology Physiology
Review published
December 18, 2025
Preprint server
bioRxiv
Darkcyan Crow reviewed
Shaker it OFF: Biophysical Characterization of an Inactivating Potassium Conductance Mediating Object Segmentation in a Collision-Detecting Neuron
Cellular and Molecular Neuroscience Ecology, Evolution, Behavior and Systematics Insect Science
Review published
December 18, 2025
Preprint server
bioRxiv
Yan Li and 1 other author reviewed
Insulin resistance alters cortical inhibitory neurons and microglia to exacerbate Alzheimer’s knock-in mouse phenotypes
Molecular Biology Physiology
Review published
December 17, 2025
Preprint server
bioRxiv
Cori Fain and John Harty reviewed
Divergent ontogeny of Tissue Resident Memory and Tissue Resident Exhausted CD8+ T cells underlies distinct functional potential
Review published
December 17, 2025
Preprint server
bioRxiv
Xue Deng reviewed
Insulin resistance alters cortical inhibitory neurons and microglia to exacerbate Alzheimer’s knock-in mouse phenotypes
Molecular Biology Physiology
Review published
December 17, 2025
Preprint server
bioRxiv
Teal Mongoose reviewed
Structural Basis of Cold and Menthol Sensing by TRPM8
Review published
December 17, 2025
Preprint server
bioRxiv
Indigo Llama and Lisa Giocomo reviewed
Grid cells encode reward distance during path integration in cue-rich environments
Cognitive Neuroscience Cellular and Molecular Neuroscience Behavioral Neuroscience
Review published
December 16, 2025
Preprint server
bioRxiv
Christian D. Castro reviewed
Disruption of Iron Metabolism Resulting from Dmt1/Slc11A2 Deficiency Compromises Notch Protein Degradation and Transcriptional Activation
Clinical Biochemistry Molecular Biology Physiology
Review published
December 16, 2025
Preprint server
bioRxiv
Rasika Ragini Iyer reviewed
Sex-Dependent Vulnerability to PTSD-Like Behaviors in iNOS Knockout Mice
Behavioral Neuroscience Biological Psychiatry
Review published
December 16, 2025
Preprint server
bioRxiv
Bronze Crab 0 reviewed
Structural Basis of Cold and Menthol Sensing by TRPM8
Review published
December 15, 2025
Preprint server
bioRxiv
Shadow Mongoose reviewed
Developmental analysis of the cone photoreceptor-less little skate retina
Molecular Biology Cellular and Molecular Neuroscience Materials Chemistry
Review published
December 15, 2025
Preprint server
bioRxiv
Chao Zhang reviewed
Context-dependent presynaptic inhibition of somatostatin interneuron inputs to Layer 1 of the visual cortex
Cognitive Neuroscience Cellular and Molecular Neuroscience
Review published
December 15, 2025
Preprint server
bioRxiv
Seagreen Snake reviewed
Developmental analysis of the cone photoreceptor-less little skate retina
Molecular Biology Cellular and Molecular Neuroscience Materials Chemistry
Review published
December 15, 2025
Preprint server
bioRxiv
Turquoise Dog reviewed
Odour representations supporting ethology-relevant categorisation and discrimination in the Drosophila mushroom body
Cellular and Molecular Neuroscience Genetics Insect Science
Review published
December 14, 2025
Preprint server
bioRxiv
Brown Owl reviewed
Odour representations supporting ethology-relevant categorisation and discrimination in the Drosophila mushroom body
Cellular and Molecular Neuroscience Genetics Insect Science
Review published
December 14, 2025
Preprint server
bioRxiv
Hickory Gorilla reviewed
Context rescales a social action code in a hormone-sensitive network
Social Psychology Ecology, Evolution, Behavior and Systematics Genetics
Review published
December 13, 2025
Preprint server
bioRxiv
Kyu Hyun Lee reviewed
Multiplexing behavioral signals in sensory representations
Cognitive Neuroscience Cellular and Molecular Neuroscience
Review published
December 12, 2025
Preprint server
bioRxiv
Yasmeen M. F. Hamed and 1 other author reviewed
PIEZO channels link mechanical forces to uterine contractions in parturition
Obstetrics and Gynecology Pediatrics, Perinatology and Child Health Reproductive Medicine
Review published
December 11, 2025
Preprint server
bioRxiv
Aliceblue Moose reviewed
WAChRs are excitatory opsins sensitive to indoor lighting
Cellular and Molecular Neuroscience Endocrine and Autonomic Systems Cognitive Neuroscience
Review published
December 11, 2025
Preprint server
bioRxiv
Sekun Park and Richard Palmiter reviewed
Semaglutide drives weight loss through cAMP-dependent mechanisms in GLP1R-expressing hindbrain neurons
Endocrinology, Diabetes and Metabolism Surgery Endocrine and Autonomic Systems
Review published
December 11, 2025
Preprint server
bioRxiv
Skyblue Gorilla and 1 other author reviewed
Central Amygdala Neuronal Ensembles Coordinate Visceral Pain and Its Affective Behaviors
Physiology Behavioral Neuroscience
Review published
December 10, 2025
Preprint server
bioRxiv
Shadow Wolf reviewed
Protein Synthesis Blockade Prevents Fear Memory Reactivation via Inhibition of Engram Synapse Strengthening
Molecular Biology Biophysics
Review published
December 8, 2025
Preprint server
bioRxiv
Donghoon Shin and Loren Frank reviewed
Large sharp-wave ripples promote hippocampo-cortical memory reactivation and consolidation
Cognitive Neuroscience Cellular and Molecular Neuroscience
Review published
December 6, 2025
Preprint server
bioRxiv
Cristina Marie Rivera Quiles and 1 other author reviewed
Incubation of oxycodone craving is associated with CP-AMPAR upregulation in D1 and D2 receptor-expressing medium spiny neurons in nucleus accumbens core and shell
Physiology Anesthesiology and Pain Medicine Pediatrics, Perinatology and Child Health
Review published
December 5, 2025
Preprint server
bioRxiv
sara bernardez noya and 1 other author reviewed
Circadian control of dopaminergic signaling to the mushroom body regulates sleep through rhythmic Pka-C1 transcription in Drosophila
Cellular and Molecular Neuroscience Endocrine and Autonomic Systems Genetics
Review published
December 4, 2025
Preprint server
bioRxiv
Rebecca Moore reviewed
Cytokine control of systemic hypoxia tolerance in Drosophila
Review published
December 3, 2025
Preprint server
bioRxiv
Joshua Raji and Christopher Potter reviewed
A Signaling Hub in the Mosquito Rectum Coordinates Reproductive Investment After Blood Feeding
Cellular and Molecular Neuroscience Insect Science
Review published
December 2, 2025
Preprint server
bioRxiv
Adelina Grusca and Ian Maze reviewed
Epigenetic Adaptation Drives Monocyte Differentiation into Microglia-Like Cells Upon Engraftment into the Central Nervous System
Review published
December 1, 2025
Preprint server
bioRxiv
Jade Crow reviewed
Neural representation of action symbols in primate frontal cortex
Social Psychology Cognitive Neuroscience
Review published
September 29, 2025
Preprint server
bioRxiv
Navyblue Chinchilla reviewed
Drosophila learn to prefer immobile spherical objects through repeated physical interaction
Ecology, Evolution, Behavior and Systematics Cellular and Molecular Neuroscience Genetics
Review published
September 22, 2025
Preprint server
bioRxiv
He Yang and 1 other author reviewed
Drosophila learn to prefer immobile spherical objects through repeated physical interaction
Ecology, Evolution, Behavior and Systematics Cellular and Molecular Neuroscience Genetics
Review published
September 18, 2025
Preprint server
bioRxiv
Malan Silva and 1 other author reviewed
Nucleus softens during herpesvirus infection
Review published
September 16, 2025
Preprint server
bioRxiv
Dalia Ornelas-Huerta and 2 other authors reviewed
A novel rhodopsin-based voltage indicator for simultaneous two-photon optical recording with GCaMP in vivo
Cellular and Molecular Neuroscience Bioengineering
Review published
September 15, 2025
Preprint server
bioRxiv
Raghabendra Adhikari and 1 other author reviewed
Targeting ZNRF3 and RNF43 to Restore Regeneration and Reverse Metabolic Dysfunction-Associated Steatotic Liver Disease
Epidemiology Hepatology Cell Biology
Review published
September 15, 2025
Preprint server
bioRxiv
Diptodip Deb reviewed
Adaptive optical correction forin vivo two-photon fluorescence microscopy with neural fields
Biophysics Biomedical Engineering
Review published
September 13, 2025
Preprint server
bioRxiv
Lilac Swan 0 reviewed
The gut-brain vagal axis governs mesolimbic dopamine dynamics and reward events
Pharmacology Neurology Endocrine and Autonomic Systems
Review published
September 8, 2025
Preprint server
bioRxiv
Ink Pelican reviewed
Insulin-like peptide secretion is mediated by peroxisome-Golgi interplay
Physiology Surgery Molecular Biology
Review published
September 8, 2025
Preprint server
bioRxiv
Shadow Deer reviewed
Co-release of opposing signaling molecules controls the escalation and release of aggression
Molecular Biology Biological Psychiatry Neurology
Review published
September 6, 2025
Preprint server
bioRxiv
E Angelo Morales and Shaohe Wang reviewed
A TRPV4-dependent calcium signaling axis governs lamellipodial actin architecture to promote cell migration
Review published
August 29, 2025
Preprint server
bioRxiv
Beige Bear reviewed
Cyanobacteria form a procarboxysome-like structure in response to high CO2
Plant Science Renewable Energy, Sustainability and the Environment Molecular Biology
Review published
August 5, 2024
Preprint server
bioRxiv
Beige Bear reviewed
Engineering the cyanobacterial ATP-driven BCT1 bicarbonate transporter for functional targeting to C3 plant chloroplasts
Review published
August 2, 2024
Preprint server
bioRxiv
Pink Deer reviewed
Mitochondrial ATP synthesis is essential for efficient gametogenesis inPlasmodium falciparum
Plant Science Parasitology Molecular Biology
Review published
July 18, 2024
Preprint server
bioRxiv
Pink Deer reviewed
REL2 overexpression in theAnopheles gambiae midgut causes major transcriptional changes but fails to induce an immune response
Immunology Insect Science Public Health, Environmental and Occupational Health
Review published
July 18, 2024
Preprint server
bioRxiv
William Grubbe and 1 other author reviewed
Structural basis for CCR6 modulation by allosteric antagonists
Radiology, Nuclear Medicine and Imaging Molecular Biology Computational Theory and Mathematics
Review published
July 18, 2024
Preprint server
bioRxiv
Rose Bird reviewed
REL2 overexpression in theAnopheles gambiae midgut causes major transcriptional changes but fails to induce an immune response
Immunology Insect Science Public Health, Environmental and Occupational Health
Review published
July 18, 2024
Preprint server
bioRxiv
Rose Bird reviewed
Mitochondrial ATP synthesis is essential for efficient gametogenesis inPlasmodium falciparum
Plant Science Parasitology Molecular Biology
Review published
July 18, 2024
Preprint server
bioRxiv
Philipp Ross and 1 other author reviewed
Aging represses lung tumorigenesis and alters tumor suppression
Cancer Research Molecular Biology
Review published
July 16, 2024
Preprint server
bioRxiv
Youchen Guan reviewed
Senolytics enhance longevity inCaenorhabditis elegans by altering betaine metabolism
Aging Endocrine and Autonomic Systems Physiology
Review published
July 5, 2024
Preprint server
bioRxiv
Lang Ding reviewed
Senolytics enhance longevity inCaenorhabditis elegans by altering betaine metabolism
Aging Endocrine and Autonomic Systems Physiology
Review published
July 5, 2024
Preprint server
bioRxiv
Lang Ding reviewed
Bacterial RNA promotes proteostasis through inter-tissue communication inC. elegans
Aging Plant Science Molecular Biology
Review published
July 5, 2024
Preprint server
bioRxiv
Youchen Guan reviewed
Bacterial RNA promotes proteostasis through inter-tissue communication inC. elegans
Aging Plant Science Molecular Biology
Review published
July 4, 2024
Preprint server
bioRxiv
Samantha Lish reviewed
Mechanochemical bistability of intestinal organoids enables robust morphogenesis
Review published
July 2, 2024
Preprint server
arXiv
Samantha Lish reviewed
On the role of mechanical feedback in synchronous to asynchronous transition during embryogenesis
Condensed Matter Physics Cell Biology Modeling and Simulation
Review published
July 2, 2024
Preprint server
arXiv
S. Chan Baek reviewed
Potential pandemic risk of circulating swine H1N2 influenza viruses
Epidemiology Agronomy and Crop Science
Review published
June 16, 2024
Preprint server
bioRxiv
Philipp Ross , William Grubbe , and 1 other author reviewed
Indels allow antiviral proteins to evolve functional novelty inaccessible by missense mutations
Virology Immunology Molecular Biology
Review published
June 14, 2024
Preprint server
bioRxiv
Philipp Ross , William Grubbe , and 1 other author reviewed
Cryo-EM structure and biochemical analysis of human chemokine receptor CCR8
Oncology Molecular Biology Radiology, Nuclear Medicine and Imaging
Review published
June 13, 2024
Preprint server
bioRxiv
Hickory Butterfly and 1 other author reviewed
Timing of transcription controls the selective translation of newly synthesized mRNAs during acute environmental stress
Review published
June 4, 2024
Preprint server
bioRxiv
Lawngreen Parrot and 1 other author reviewed
Timing of transcription controls the selective translation of newly synthesized mRNAs during acute environmental stress
Review published
June 4, 2024
Preprint server
bioRxiv
Navyblue Otter reviewed
Genetic architecture of inbreeding depression may explain its persistence in a population of wild red deer
Review published
June 3, 2024
Preprint server
bioRxiv
Navyblue Otter reviewed
Unraveling the genetic legacy of commercial whaling in bowhead whales and narwhals
Ecology Atmospheric Science Oceanography
Review published
June 3, 2024
Preprint server
bioRxiv
S. Chan Baek and 2 other authors reviewed
Deep mutational scanning reveals functional constraints and antigenic variability of Lassa virus glycoprotein complex
Infectious Diseases Genetics
Review published
May 17, 2024
Preprint server
bioRxiv
Obsidian Coyote and 1 other author reviewed
Divergent mechanisms of steroid inhibition in the human ρ1 GABAA receptor
Cellular and Molecular Neuroscience Biophysics Plant Science
Review published
May 8, 2024
Preprint server
bioRxiv
Lawngreen Parrot and 1 other author reviewed
Full-length direct RNA sequencing uncovers stress-granule dependent RNA decay upon cellular stress
Review published
April 20, 2024
Preprint server
bioRxiv
Hickory Butterfly and 1 other author reviewed
Full-length direct RNA sequencing uncovers stress-granule dependent RNA decay upon cellular stress
Review published
April 19, 2024
Preprint server
bioRxiv
Luisa Vasconcelos and ROY PARKER reviewed
Cytoplasmic protein-free mRNA induces stress granules by two G3BP1/2-dependent mechanisms
Review published
March 25, 2024
Preprint server
bioRxiv
Liyi Cheng and ROY PARKER reviewed
Cytoplasmic protein-free mRNA induces stress granules by two G3BP1/2-dependent mechanisms
Review published
March 25, 2024
Preprint server
bioRxiv
James Fraser , Luisa Vasconcelos , Liyi Cheng , Samantha Lish , S. Chan Baek , Lang Ding , Alexandra Probst , Naiya Phillips , William Grubbe , Youchen Guan , and 2 other authors reviewed
Virion morphology and on-virus spike protein structures of diverse SARS-CoV-2 variants
Infectious Diseases Ecology
Review published
March 4, 2024
Preprint server
bioRxiv