End-stage chronic kidney disease (CKD) and its treatment by hemodialysis represent a public health issue especially in Morocco. This study aimed to assess the impact of chronic renal failure on oral health in patients undergoing renal dialysis. A cross-sectional study was conducted among patients undergoing dialysis. The variables recorded were DMFT index and pH salivary. The correlation between oral health and the duration of dialysis was assessed. A total of 46 adult hemodialysis was evaluated, among them 52.2% were males, the mean age was 58.72 ± 12.4 years. All the patients in the sample underwent three dialysis sessions per week. Half of the patients brushed their teeth once a day. The average DMF-T index was 15.41 ± 6.04. Xerostomia was noted in 84.8% of the sample. This health situation analysis showed that dental care of the dialysis patients was not favorable, highlighting a great need for dental treatment. CKD cases should be made aware of the oral problems and their potential effect on overall health. A multidisciplinary approach with the involvement of different specialties is recommended.