Present a pedagogical scenography model, Inside the Blood, discuss aspects of the circulation and blood elements in healthy and disease conditions. The visitors walk inside an ArtScience installation as if they were “inside a blood vessel” through the immersive and sensorial experience. The visit was mediated by an educator discussing some aspects of the acute phase, when the parasite called Trypanosoma cruzi is found in the blood of infected people, attracting attention of distinct ages and scholar levels. To understand and evaluate the construction of knowledge through the eyes of visitors, they created models in a modelling clay art craft workshop. More than 80% of the clay models expressed information about scientific content and 66% presents association between scientific information and subjective messages with personal meanings. We concluded that the model is a useful tool for science and health education, aiming to create artistic expressions that potentialize learnings and communication.