PREreview of Combination Therapy in Hypertension: Renin-Angiotensin-Aldosterone System Inhibitor with a Diuretic or Calcium Channel Blocker

 This paper’s goal was to comparatively analysis the most frequently used combination: RAAS inhibitor with diuretics or a calcium channel blocker. This is a very good study because combination therapy is better than one therapy. The topic is relevant and addresses significant public health issues. However, the abstract talks mainly about the background and does not balance with other sections, such as methods, results, and conclusions.

Methods

I am not sure what methods were used to arrive at the presented findings, as this is not clear in the manuscript. I would appreciate it if the author could clarify this clearly, providing details on sampling methods, inclusion, and exclusion criteria. This will help clarify other sections of the manuscript. 

Competing interests

The authors declare that they have no competing interests.

Use of Artificial Intelligence (AI)

The authors declare that they did not use generative AI to come up with new ideas for their review.