Structured PREreview of Golden rules for building sustainable bioinformatics capacity using Nextflow and nf-core with a focus on early-mid career researchers: The Kids Research Institute Australia, case report.

Does the introduction explain the objective of the research presented in the preprint?

Yes

The introduction is clear. The issue is explained (the surge in demand for bioinformatics skills) and their proposed solution is presented, followed with their integration in an existing research group. However, there are a few grammatical and punctuation errors in the first two paragraphs that reduce the impact of the intro.

Are the methods well-suited for this research?

Highly appropriate

Are the conclusions supported by the data?

Somewhat supported

There is no quantitative data, so we have no summary statistics or quantitative analysis of participant outcomes, leaving us to rely on the descriptive evidence from the authors

Are the data presentations, including visualizations, well-suited to represent the data?

Highly appropriate and clear

Figure 1 clearly illustrated the process, and the linked GitHub page with its schedule and training materials offered valuable insight into the training provided to participants. However, in the preprint, the image is not imbedded; I think it would be beneficial to include, since it is the only image for the paper.

How clearly do the authors discuss, explain, and interpret their findings and potential next steps for the research?

Somewhat clearly

Is the preprint likely to advance academic knowledge?

Highly likely

The set of rules defined by the paper are practical and actionable, grounded in real-world institutional experience. This kind of guidance is valuable to other research centers looking to execute similar initiatives. While reading, I thought that our own institution would benefit from the same structured training to develop a baseline of skills throughout research groups.

Would it benefit from language editing?

Yes

There were a few grammatical and punctuation errors I noted in the introduction, which distracted from the reading experience.

Would you recommend this preprint to others?

Yes, it’s of high quality

The paper covers a lot of ground. From the implementation of Nextflow and nf-core in bioinformatics capacity building, while making references to community practices and relevant literature. The format of the “golden rules” provides actionable steps, and are based on real-world experience, which is valuable for institutions.

Is it ready for attention from an editor, publisher or broader audience?

Yes, after minor changes

Competing interests

The author declares that they have no competing interests.