Innovation adoption in primary sectors—agriculture, horticulture, forestry, and aquaculture—is essential for addressing pressing global challenges including climate change, resource degradation, and food security. However, a persistent gap exists between innovation potential and actual implementation, with many promising technologies failing to achieve widespread adoption despite substantial research investments. This paper presents the Extended Integrated Adoption Model Framework (EIAMF), a systemic approach that addresses critical gaps in adoption theory by integrating four quadrants: technologies, users, finance, and institutions. The EIAMF explicitly recognizes adoption as a systemic process requiring alignment across multiple dimensions. The framework’s distinctive contribution lies in its emphasis on inter-quadrant relationships, revealing how variables across different domains interact, compound, and cascade to create either enabling conditions or barriers. We demonstrate how the framework can enable practitioners to proactively identify potential adoption barriers early in the innovation development process by providing structured diagnostic protocols that reveal when barriers in multiple quadrants compound to create obstacles, when cascade effects amplify constraints across the system, and where strategic interventions can address multiple barriers simultaneously. We discuss theoretical contributions and practical implications for practitioners and policy designers, highlighting how the EIAMF provides stakeholders with a tool for designing more effective adoption strategies.