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Urinary Bladder Hamartoma: First Reported Case in Germany and Literature Review of a Rare Benign Lesion

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Preprints.org
DOI
10.20944/preprints202506.1853.v2

This article covers a rare, benign tumor called hamartoma of the urinary bladder, made up of disorganized but normal bladder tissues like urothelium, fibrous stroma, smooth muscle, and fat. It lacks malignant features such as cellular atypia or necrosis. Patients often present with lower urinary tract symptoms (LUTS) and hematuria. Bladder hamartomas have been linked to syndromes like Peutz-Jeghers. Treatment typically involves transurethral resection, with rare recurrence; partial cystectomy is occasionally needed. This case report details the first known case in Germany and the 16th globally, involving a young patient, and includes a thorough literature review.

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