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| Question | Yes | Unsure | N/A | No |
|---|---|---|---|---|
| Are the findings novel? | 100% | 0% | 0% | 0% |
| Are the results likely to lead to future research? | 100% | 0% | 0% | 0% |
| Is sufficient detail provided to allow reproduction of the study? | 100% | 0% | 0% | 0% |
| Are the methods and statistics appropriate for the analysis? | 100% | 0% | 0% | 0% |
| Are the principal conclusions supported by the data and analysis? | 100% | 0% | 0% | 0% |
| Does the manuscript discuss limitations? | 0% | 0% | 0% | 100% |
| Have the authors adequately discussed ethical concerns? | 0% | 0% | 100% | 0% |
| Does the manuscript include new data? | 100% | 0% | 0% | 0% |
| Are the data used in the manuscript available? | 0% | 0% | 100% | 0% |
| Is the code used in the manuscript available? | 0% | 0% | 100% | 0% |
| Would you recommend this manuscript to others? | 100% | 0% | 0% | 0% |
| Do you recommend this manuscript for peer review? | 0% | 0% | 100% | 0% |
In this manuscript, Ting et al. describe three gene clusters - named antagonism resistance clusters (arc1-3) - that are upregulated by the Gac/Rsm danger sensing system and proposed to work as an innate immunity system against antibacterial attacks. This work builds on their previous studies …